Published : Jun-2017
No. of Pages : 80
1 Table of Contents 2
1.1 List of Tables 4
1.2 List of Figures 5
2 Introduction 6
2.1 Viscosupplementation Devices Overview 6
3 Products under Development 7
3.1 Viscosupplementation Devices - Pipeline Products by Stage of Development 7
3.2 Viscosupplementation Devices - Pipeline Products by Segment 8
3.3 Viscosupplementation Devices - Pipeline Products by Territory 9
3.4 Viscosupplementation Devices - Pipeline Products by Regulatory Path 10
3.5 Viscosupplementation Devices - Pipeline Products by Estimated Approval Date 11
3.6 Viscosupplementation Devices - Ongoing Clinical Trials 12
4 Viscosupplementation Devices - Pipeline Products under Development by Companies 13
4.1 Viscosupplementation Devices Companies - Pipeline Products by Stage of Development 13
4.2 Viscosupplementation Devices - Pipeline Products by Stage of Development 14
5 Viscosupplementation Devices Companies and Product Overview 15
5.1 Ampio Pharmaceuticals Inc Company Overview 15
5.1.1 Ampio Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 15
5.2 Anika Therapeutics Inc Company Overview 18
5.2.1 Anika Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 18
5.3 BioTime Inc Company Overview 23
5.3.1 BioTime Inc Pipeline Products & Ongoing Clinical Trials Overview 23
5.4 Bioventus LLC Company Overview 25
5.4.1 Bioventus LLC Pipeline Products & Ongoing Clinical Trials Overview 25
5.5 Carticept Medical, Inc. Company Overview 26
5.5.1 Carticept Medical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 26
5.6 Chi2Gel Ltd. Company Overview 27
5.6.1 Chi2Gel Ltd. Pipeline Products & Ongoing Clinical Trials Overview 27
5.7 Cocoon Biotech, Inc. Company Overview 28
5.7.1 Cocoon Biotech, Inc. Pipeline Products & Ongoing Clinical Trials Overview 28
5.8 DePuy Synthes Inc Company Overview 29
5.8.1 DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 29
5.9 Flex Biomedical Inc Company Overview 30
5.9.1 Flex Biomedical Inc Pipeline Products & Ongoing Clinical Trials Overview 30
5.10 Hanmi Pharmaceuticals Co Ltd Company Overview 31
5.10.1 Hanmi Pharmaceuticals Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 31
5.11 Kalvista Pharmaceuticals Inc Company Overview 33
5.11.1 Kalvista Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 33
5.12 Moebius Medical Ltd Company Overview 36
5.12.1 Moebius Medical Ltd Pipeline Products & Ongoing Clinical Trials Overview 36
5.13 OPKO Health Inc Company Overview 37
5.13.1 OPKO Health Inc Pipeline Products & Ongoing Clinical Trials Overview 37
5.14 Shanghai Haohai Biological Technology Co Ltd Company Overview 38
5.14.1 Shanghai Haohai Biological Technology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 38
5.15 Spring Therapeutics Company Overview 39
5.15.1 Spring Therapeutics Pipeline Products & Ongoing Clinical Trials Overview 39
5.16 Synolyne Pharma Company Overview 40
5.16.1 Synolyne Pharma Pipeline Products & Ongoing Clinical Trials Overview 40
5.17 University of Kansas Company Overview 41
5.17.1 University of Kansas Pipeline Products & Ongoing Clinical Trials Overview 41
6 Viscosupplementation Devices - Recent Developments 42
6.1 May 08, 2017: HYMOVIS: An Innovation in HA-Based Viscoelastic Hydrogel Technology in the Treatment of Osteoarthritis Knee Pain 42
6.2 May 05, 2017: Smith & Nephew 2017 First Quarter Trading Report 42
6.3 May 03, 2017: Anika Reports First Quarter 2017 Financial Results 44
6.4 Apr 28, 2017: Lennart Johansson to Join BONESUPPORT Board of Directors 45
6.5 Apr 24, 2017: Bioventus Names David Varner Vice President of Marketing, Active Healing Therapies 45
6.6 Apr 11, 2017: BONESUPPORT Appoints Michael Diefenbeck as Chief Medical Officer 46
6.7 Mar 22, 2017: HYMOVIS Demonstrates Superior Biomechanical Lubricating Properties 46
6.8 Mar 20, 2017: Ampio Pharmaceuticals Provides Corporate Update 47
6.9 Mar 16, 2017: KalVista Pharmaceuticals Reports Fiscal Third Quarter Results 47
6.10 Mar 09, 2017: KalVista Pharmaceuticals Appoints Dr. Andreas Maetzel Senior Vice President of Medical 48
6.11 Feb 27, 2017: Ampio Receives Guidance from the FDA and Proposes a Path for Approval for Single-Injection Ampion for the Treatment of Pain Due to Severe Osteoarthritis of the Knee 49
6.12 Feb 15, 2017: Anika Reports Fourth Quarter and Full Year 2016 Financial Results 49
6.13 Feb 15, 2017: Anika Therapeutics Reports 33% Revenue Growth in Third Quarter 2011 50
6.14 Feb 09, 2017: Smith & Nephew Fourth Quarter Trading and Full Year 2016 Results 51
6.15 Feb 09, 2017: Smith & Nephew: Directorate Change 57
6.16 Feb 08, 2017: OPKO Spain to Start Trial of Once-A-Year Intra-Articular Injectable for Osteoarthritis 57
6.17 Feb 03, 2017: SEIKAGAKU: Consolidated Financial Results for the First Nine Months of Fiscal 2016 57
6.18 Feb 01, 2017: Zimmer Biomet Announces FDA Approval of Expanded 26-week Efficacy Claim for Gel-One Cross-Linked Hyaluronate for Treatment of Pain Associated with Knee Osteoarthritis 59
6.19 Jan 17, 2017: Bioventus Selects MEDSERVICE to Distribute DUROLANE in Russia 59
6.20 Jan 12, 2017: Confirmation of CFO leaving Smith & Nephew 60
6.21 Jan 06, 2017: BONESUPPORT CEO Richard Davies to present at Medtech Showcase 2017 60
6.22 Dec 21, 2016: Bjorn Westberg to Join BONESUPPORT as Chief Financial Officer 60
6.23 Dec 20, 2016: Appointment of Nestle Skin Health CEO ad interim 61
6.24 Dec 19, 2016: Anika Wins CE Mark Approval For ORTHOVISC-T To Relieve Pain and Restore Function of Tendons Damaged by Chronic Injury 61
6.25 Dec 16, 2016: BONESUPPORT Confirms Election of Dr. Hakan Bjorklund as Chairman of the Board 62
6.26 Nov 30, 2016: Graham Baker appointed Chief Financial Officer 62
6.27 Nov 14, 2016: Bioventus Expands to Mexico with DUROLANE for Knee Osteoarthritis Patients 63
6.28 Nov 10, 2016: HYMOVIS Receives Permanent, Product-Specific J-Code from the Center for Medicare and Medicaid Services 63
6.29 Nov 08, 2016: Seikagaku Announces Exclusive Distributorship Agreement in the U.S. for VISCO-3, A Three-Injection Viscosupplement Product 64
6.30 Nov 07, 2016: Bioventus Appoints Andrew McCartney Managing Director, International for EMEA 64
6.31 Nov 07, 2016: BONESUPPORT Announces Key Corporate Appointment To Drive Growth In North America 65
6.32 Nov 03, 2016: Lattice Biologics Inks Strategic Partnerships With OA Centers of America, Resilience, and Cryoport 65
6.33 Nov 03, 2016: Smith & Nephew Third Quarter 2016 Trading Report 66
6.34 Oct 26, 2016: Anika Reports Third Quarter 2016 Financial Results 67
6.35 Aug 30, 2016: Ampio Reports Additional Peer-Reviewed Publication on Ampion 68
6.36 Aug 03, 2016: Ampio Updates Regulatory Status Of AMPION 69
6.37 Jul 28, 2016: Smith & Nephew Second Quarter Trading and First Half 2016 Results 69
6.38 Jul 27, 2016: Anika Reports Second Quarter 2016 Financial Results 72
6.39 Jul 11, 2016: CFO to leave Smith & Nephew in early 2017 73
6.40 Jul 05, 2016: Fidia Presents New Data on Hymovis, a Breakthrough in Viscoelastic Technology, at the American Orthopaedic Society for Sports Medicine 2016 Annual Meeting 73
6.41 Jul 01, 2016: Bioventus Extends Distribution Agreement for SUPARTZ FX 74
6.42 Jun 30, 2016: Ampio Announces Results of Ampion Trials 74
6.43 Jun 24, 2016: Michael Minogue Named to Bioventus Board of Managers 75
7 Appendix 77
7.1 Methodology 77
7.2 About GlobalData 80
7.3 Contact Us 80
7.4 Disclaimer 80
1.1 List of Tables
Table 1: Viscosupplementation Devices - Pipeline Products by Stage of Development 7
Table 2: Viscosupplementation Devices - Pipeline Products by Segment 8
Table 3: Viscosupplementation Devices - Pipeline Products by Territory 9
Table 4: Viscosupplementation Devices - Pipeline Products by Regulatory Path 10
Table 5: Viscosupplementation Devices - Pipeline Products by Estimated Approval Date 11
Table 6: Viscosupplementation Devices - Ongoing Clinical Trials 12
Table 7: Viscosupplementation Companies - Pipeline Products by Stage of Development 13
Table 8: Viscosupplementation Devices - Pipeline Products by Stage of Development 14
Table 9: Ampio Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 15
Table 10: Ampion - Product Status 15
Table 11: Ampion - Product Description 15
Table 12: Ampio Pharmaceuticals Inc - Ongoing Clinical Trials Overview 16
Table 13: Ampion - A Randomized, Pre-approval Study to Evaluate the Efficacy of Ampion in Patients with Severe Knee Osteoarthritis 17
Table 14: Anika Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 18
Table 15: Cingal - Product Status 18
Table 16: Cingal - Product Description 19
Table 17: MONOVISC - Product Status 19
Table 18: MONOVISC - Product Description 19
Table 19: MONOVISC - Hip - Product Status 20
Table 20: MONOVISC - Hip - Product Description 20
Table 21: ORTHOVISC-T - Product Status 20
Table 22: ORTHOVISC-T - Product Description 21
Table 23: Anika Therapeutics Inc - Ongoing Clinical Trials Overview 22
Table 24: MONOVISC - Hip - Investigational Device Exemption (IDE) Phase III Study of MONOVISC to Treat Pain Caused by Osteoarthritis of the Hip 22
Table 25: BioTime Inc Pipeline Products & Ongoing Clinical Trials Overview 23
Table 26: ReGlyde - Product Status 23
Table 27: ReGlyde - Product Description 24
Table 28: Bioventus LLC Pipeline Products & Ongoing Clinical Trials Overview 25
Table 29: Supartz 3 - Product Status 25
Table 30: Supartz 3 - Product Description 25
Table 31: Carticept Medical, Inc. Pipeline Products & Ongoing Clinical Trials Overview 26
Table 32: Agilus - Product Status 26
Table 33: Agilus - Product Description 26
Table 34: Chi2Gel Ltd. Pipeline Products & Ongoing Clinical Trials Overview 27
Table 35: Chi2Knee - Product Status 27
Table 36: Chi2Knee - Product Description 27
Table 37: Cocoon Biotech, Inc. Pipeline Products & Ongoing Clinical Trials Overview 28
Table 38: Silk Hydrogel - Product Status 28
Table 39: Silk Hydrogel - Product Description 28
Table 40: DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 29
Table 41: Platelet Rich Plasma System - Product Status 29
Table 42: Platelet Rich Plasma System - Product Description 29
Table 43: Flex Biomedical Inc Pipeline Products & Ongoing Clinical Trials Overview 30
Table 44: Flex Polymer - Product Status 30
Table 45: Flex Polymer - Product Description 30
Table 46: Hanmi Pharmaceuticals Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 31
Table 47: Hyalrheuma - Product Status 31
Table 48: Hyalrheuma - Product Description 31
Table 49: Hanmi Pharmaceuticals Co Ltd - Ongoing Clinical Trials Overview 32
Table 50: Hyalrheuma - Phase 3 Clinical Trial for Osteoarthritis Medicine Hyalrheuma 32
Table 51: Kalvista Pharmaceuticals Inc Pipeline Products & Ongoing Clinical Trials Overview 33
Table 52: ActaVisc - Product Status 33
Table 53: ActaVisc - Product Description 33
Table 54: Hydros - Product Status 34
Table 55: Hydros - Product Description 34
Table 56: Hydros TA - Product Status 34
Table 57: Hydros TA - Product Description 35
Table 58: Hydros TA - Hip - Product Status 35
Table 59: Hydros TA - Hip - Product Description 35
Table 60: Moebius Medical Ltd Pipeline Products & Ongoing Clinical Trials Overview 36
Table 61: MM-II - Product Status 36
Table 62: MM-II - Product Description 36
Table 63: OPKO Health Inc Pipeline Products & Ongoing Clinical Trials Overview 37
Table 64: Enko 1 - Product Status 37
Table 65: Enko 1 - Product Description 37
Table 66: Shanghai Haohai Biological Technology Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 38
Table 67: Thermal-Sensitive Chitosan Gel - Product Status 38
Table 68: Thermal-Sensitive Chitosan Gel - Product Description 38
Table 69: Spring Therapeutics Pipeline Products & Ongoing Clinical Trials Overview 39
Table 70: CA-5136 - Product Status 39
Table 71: CA-5136 - Product Description 39
Table 72: Synolyne Pharma Pipeline Products & Ongoing Clinical Trials Overview 40
Table 73: Arthrovisc - Product Status 40
Table 74: Arthrovisc - Product Description 40
Table 75: University of Kansas Pipeline Products & Ongoing Clinical Trials Overview 41
Table 76: 3-D Colloidal Gel - Product Status 41
Table 77: 3-D Colloidal Gel - Product Description 41
Table 78: Glossary 79
1.2 List of Figures
Figure 1: Viscosupplementation Devices - Pipeline Products by Stage of Development 7
Figure 2: Viscosupplementation Devices - Pipeline Products by Segment 8
Figure 3: Viscosupplementation Devices - Pipeline Products by Territory 9
Figure 4: Viscosupplementation Devices - Pipeline Products by Regulatory Path 10
Figure 5: Viscosupplementation Devices - Pipeline Products by Estimated Approval Date 11
Figure 6: Viscosupplementation Devices - Ongoing Clinical Trials 12
