Summary
Global Markets Direct’s, ‘Migraine – Pipeline Review, H1 2012’, provides an overview of the Migraine therapeutic pipeline. This report provides information on the therapeutic development for Migraine, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Migraine. ‘Migraine – Pipeline Review, H1 2012’ is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team.
Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.
Scope
– A snapshot of the global therapeutic scenario for Migraine.
– A review of the Migraine products under development by companies and universities/research institutes based on information derived from company and industry-specific sources.
– Coverage of products based on various stages of development ranging from discovery till registration stages.
– A feature on pipeline projects on the basis of monotherapy and combined therapeutics.
– Coverage of the Migraine pipeline on the basis of route of administration and molecule type.
– Profiles of late-stage pipeline products featuring sections on product description, mechanism of action and research & development progress.
– Key discontinued pipeline projects.
– Latest news and deals relating to the products.
Reasons to buy
– Identify and understand important and diverse types of therapeutics under development for Migraine.
– Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive advantage.
– Plan mergers and acquisitions effectively by identifying players with the most promising pipeline.
– Devise corrective measures for pipeline projects by understanding Migraine pipeline depth and focus of Migraine therapeutics.
– Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
– Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline.
Migraine Pipeline Trial
Published: February 2012
No. of Pages: 145
Price:US$500
Table of Contents
Table of Contents 2
List of Tables 5
List of Figures 6
Introduction 7
Global Markets Direct Report Coverage 7
Migraine Overview 8
Therapeutics Development 9
An Overview of Pipeline Products for Migraine 9
Migraine Therapeutics under Development by Companies 11
Migraine Therapeutics under Investigation by Universities/Institutes 15
Late Stage Products 18
Comparative Analysis 18
Mid Clinical Stage Products 19
Comparative Analysis 19
Early Clinical Stage Products 20
Comparative Analysis 20
Discovery and Pre-Clinical Stage Products 21
Comparative Analysis 21
Migraine Therapeutics – Products under Development by Companies 22
Migraine Therapeutics – Products under Investigation by Universities/Institutes 23
Companies Involved in Migraine Therapeutics Development 24
Sanofi-Aventis 24
Vyteris, Inc. 25
Eli Lilly and Company 26
Vectura Group plc 27
Biofrontera AG 28
Novartis AG 29
Axcan Pharma Inc. 30
Eisai Co., Ltd. 31
Pfizer Inc. 32
Teva Pharmaceutical Industries Limited 33
NuPathe Inc. 34
Capnia, Inc. 35
IntelGenx Technologies Corp. 36
NovaDel Pharma, Inc. 37
Paladin Labs Inc. 38
MAP Pharmaceuticals, Inc. 39
POZEN Inc. 40
Asterand plc. 41
Genizon BioSciences, Inc. 42
D-Pharm Ltd. 43
Physica Pharma 44
MIKA Pharma GmbH 45
Ache Laboratorios Farmaceuticos S/A 46
CoLucid Pharmaceuticals, Inc. 47
Pantarhei Bioscience BV 48
NeurAxon, Inc. 49
Winston Pharmaceuticals, Inc. 50
The EMMES Corporation 51
Trigemina, Inc. 52
Migraine – Therapeutics Assessment 53
Assessment by Monotherapy Products 53
Assessment by Combination Products 54
Assessment by Route of Administration 55
Assessment by Molecule Type 57
Drug Profiles 59
E2007 – Drug Profile 59
Levadex – Drug Profile 61
EUR 1000 – Drug Profile 63
BF-1 – Drug Profile 64
MK49 – Drug Profile 65
Sumatriptan SDI – Drug Profile 66
PHY 303 – Drug Profile 67
Estetrol – Drug Profile 68
INT0008 – Drug Profile 70
Zolmitriptan – Drug Profile 71
MT 400 – Drug Profile 72
NXN-188 – Drug Profile 74
NXN-462 – Drug Profile 75
nNOS/NET – Drug Profile 76
VR147 – Drug Profile 77
Nasal Carbon Dioxide – Drug Profile 78
NVD-201 – Drug Profile 79
DP-VPA – Drug Profile 80
Candesartan Cilexitil – Drug Profile 82
BGG492 – Drug Profile 83
TI-001 – Drug Profile 85
PF-04427429 – Drug Profile 86
LY2951742 – Drug Profile 87
Metoclopramide – Drug Profile 88
Topiramate – Drug Profile 89
Sodium Valporate – Drug Profile 90
Zelrix – Drug Profile 91
Enalapril – Drug Profile 93
COL-144 – Drug Profile 94
Topiramate + Propranolol – Drug Profile 95
N-Alpha Methyl Histamine – Drug Profile 97
Compazine – Drug Profile 98
Ethosuximide – Drug Profile 99
Metoclopramide + Ketoprofen – Drug Profile 100
BGC20-1531 – Drug Profile 101
Caffeine + Propranolol – Drug Profile 102
Longevity Program – Drug Profile 103
DR-105 – Drug Profile 104
Ketoprofen – Drug Profile 105
Cyclobenzaprine Hydrochloride Extended Release – Drug Profile 106
Dolorac – Drug Profile 107
LY2300559 – Drug Profile 108
Propofol – Drug Profile 109
Dexamethasone – Drug Profile 110
DIS-COM-TRO – Drug Profile 111
RHB-103 – Drug Profile 112
R101 – Drug Profile 113
Simvastatin + Vitamin D – Drug Profile 114
Naratriptan + Naproxen – Drug Profile 115
Topiramate – Drug Profile 116
Topiramate – Drug Profile 117
Ibuprofen + Caffeine – Drug Profile 118
Migraine Therapeutics – Drug Profile Updates 119
Migraine Therapeutics – Discontinued Products 129
Migraine Therapeutics – Dormant Products 130
Migraine – Product Development Milestones 131
Featured News & Press Releases 131
Appendix 140
Methodology 140
Coverage 140
Secondary Research 140
Primary Research 140
Expert Panel Validation 141
Contact Us 141
Disclaimer 141
List of Tables
Number of Products Under Development for Migraine, H1 2012 13
Products under Development for Migraine – Comparative Analysis, H1 2012 14
Number of Products under Development by Companies, H1 2012 16
Number of Products under Development by Companies, H1 2012 (Contd..1) 17
Number of Products under Development by Companies, H1 2012 (Contd..2) 18
Number of Products under Investigation by Universities/Institutes, H1 2012 20
Number of Products under Investigation by Universities/Institutes, H1 2012 (Contd..1) 21
Comparative Analysis by Late Stage Development, H1 2012 22
Comparative Analysis by Mid Clinical Stage Development, H1 2012 23
Comparative Analysis by Early Clinical Stage Development, H1 2012 24
Comparative Analysis by Discovery and Pre-Clinical Stage Development, H1 2012 25
Products under Development by Companies, H1 2012 26
Products under Investigation by Universities/Institutes, H1 2012 27
Sanofi-Aventis, H1 2012 28
Vyteris, Inc., H1 2012 29
Eli Lilly and Company, H1 2012 30
Vectura Group plc, H1 2012 31
Biofrontera AG, H1 2012 32
Novartis AG, H1 2012 33
Axcan Pharma Inc., H1 2012 34
Eisai Co., Ltd., H1 2012 35
Pfizer Inc., H1 2012 36
Teva Pharmaceutical Industries Limited, H1 2012 37
NuPathe Inc., H1 2012 38
Capnia, Inc., H1 2012 39
IntelGenx Technologies Corp., H1 2012 40
NovaDel Pharma, Inc., H1 2012 41
Paladin Labs Inc., H1 2012 42
MAP Pharmaceuticals, Inc., H1 2012 43
POZEN Inc., H1 2012 44
Asterand plc., H1 2012 45
Genizon BioSciences, Inc., H1 2012 46
D-Pharm Ltd., H1 2012 47
Physica Pharma, H1 2012 48
MIKA Pharma GmbH, H1 2012 49
Ache Laboratorios Farmaceuticos S/A, H1 2012 50
CoLucid Pharmaceuticals, Inc., H1 2012 51
Pantarhei Bioscience BV, H1 2012 52
NeurAxon, Inc., H1 2012 53
Winston Pharmaceuticals, Inc., H1 2012 54
The EMMES Corporation, H1 2012 55
Trigemina, Inc., H1 2012 56
Assessment by Monotherapy Products, H1 2012 57
Assessment by Combination Products, H1 2012 58
Assessment by Stage and Route of Administration, H1 2012 60
Assessment by Stage and Molecule Type, H1 2012 62
Migraine Therapeutics – Drug Profile Updates 123
Migraine Therapeutics – Discontinued Products 133
Migraine Therapeutics – Dormant Products 134
List of Figures
Number of Products under Development for Migraine, H1 2012 13
Products under Development for Migraine – Comparative Analysis, H1 2012 14
Products under Development by Companies, H1 2012 15
Products under Investigation by Universities/Institutes, H1 2012 19
Late Stage Products, H1 2012 22
Mid Clinical Stage Products, H1 2012 23
Early Clinical Stage Products, H1 2012 24
Discovery and Pre-Clinical Stage Products, H1 2012 25
Assessment by Monotherapy Products, H1 2012 57
Assessment by Combination Products, H1 2012 58
Assessment by Route of Administration, H1 2012 59
Assessment by Stage and Route of Administration, H1 2012 60
Assessment by Molecule Type, H1 2012 61
Assessment by Stage and Molecule Type, H1 2012 62