Published : Jun-2017
No. of Pages : 263
1 Table of Contents 2
1.1 List of Tables 9
1.2 List of Figures 12
2 Introduction 13
2.1 Knee Reconstruction Overview 13
3 Products under Development 14
3.1 Knee Reconstruction - Pipeline Products by Stage of Development 14
3.2 Knee Reconstruction - Pipeline Products by Segment 15
3.3 Knee Reconstruction - Pipeline Products by Territory 16
3.4 Knee Reconstruction - Pipeline Products by Regulatory Path 17
3.5 Knee Reconstruction - Pipeline Products by Estimated Approval Date 18
3.6 Knee Reconstruction - Ongoing Clinical Trials 19
4 Knee Reconstruction - Pipeline Products under Development by Companies 20
4.1 Knee Reconstruction Companies - Pipeline Products by Stage of Development 20
4.2 Knee Reconstruction - Pipeline Products by Stage of Development 22
5 Knee Reconstruction Companies and Product Overview 24
5.1 4-Web Spine, LLC Company Overview 24
5.1.1 4-Web Spine, LLC Pipeline Products & Ongoing Clinical Trials Overview 24
5.2 Active Implants LLC Company Overview 25
5.2.1 Active Implants LLC Pipeline Products & Ongoing Clinical Trials Overview 25
5.3 Amedica Corp Company Overview 29
5.3.1 Amedica Corp Pipeline Products & Ongoing Clinical Trials Overview 29
5.4 Arcuro Medical Ltd. Company Overview 30
5.4.1 Arcuro Medical Ltd. Pipeline Products & Ongoing Clinical Trials Overview 30
5.5 ArthroSurface Inc Company Overview 31
5.5.1 ArthroSurface Inc Pipeline Products & Ongoing Clinical Trials Overview 31
5.6 Artimplant AB (Inactive) Company Overview 32
5.6.1 Artimplant AB (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 32
5.7 Aspect Biosystems Ltd Company Overview 33
5.7.1 Aspect Biosystems Ltd Pipeline Products & Ongoing Clinical Trials Overview 33
5.8 B. Braun Melsungen AG Company Overview 34
5.8.1 B. Braun Melsungen AG Pipeline Products & Ongoing Clinical Trials Overview 34
5.9 BioPoly RS LLC Company Overview 35
5.9.1 BioPoly RS LLC Pipeline Products & Ongoing Clinical Trials Overview 35
5.10 Bonovo Orthopedics Inc Company Overview 36
5.10.1 Bonovo Orthopedics Inc Pipeline Products & Ongoing Clinical Trials Overview 36
5.11 Clemson University Company Overview 37
5.11.1 Clemson University Pipeline Products & Ongoing Clinical Trials Overview 37
5.12 Corin Group Plc Company Overview 39
5.12.1 Corin Group Plc Pipeline Products & Ongoing Clinical Trials Overview 39
5.13 Ecole de technologie superieure Company Overview 42
5.13.1 Ecole de technologie superieure Pipeline Products & Ongoing Clinical Trials Overview 42
5.14 Exactech Inc Company Overview 43
5.14.1 Exactech Inc Pipeline Products & Ongoing Clinical Trials Overview 43
5.15 EZ ORTHOPEDICS ISRAEL Company Overview 48
5.15.1 EZ ORTHOPEDICS ISRAEL Pipeline Products & Ongoing Clinical Trials Overview 48
5.16 Hospital for Special Surgery Company Overview 49
5.16.1 Hospital for Special Surgery Pipeline Products & Ongoing Clinical Trials Overview 49
5.17 Indian Institute of Technology Bombay Company Overview 51
5.17.1 Indian Institute of Technology Bombay Pipeline Products & Ongoing Clinical Trials Overview 51
5.18 Invibio Inc Company Overview 52
5.18.1 Invibio Inc Pipeline Products & Ongoing Clinical Trials Overview 52
5.19 Kinamed Inc Company Overview 53
5.19.1 Kinamed Inc Pipeline Products & Ongoing Clinical Trials Overview 53
5.20 KYOCERA Medical Corp Company Overview 54
5.20.1 KYOCERA Medical Corp Pipeline Products & Ongoing Clinical Trials Overview 54
5.21 Materialise NV Company Overview 55
5.21.1 Materialise NV Pipeline Products & Ongoing Clinical Trials Overview 55
5.22 Mathys AG Bettlach Company Overview 57
5.22.1 Mathys AG Bettlach Pipeline Products & Ongoing Clinical Trials Overview 57
5.23 MicroPort Scientific Corp Company Overview 58
5.23.1 MicroPort Scientific Corp Pipeline Products & Ongoing Clinical Trials Overview 58
5.24 Moirai Orthopaedics, L.L.C. Company Overview 60
5.24.1 Moirai Orthopaedics, L.L.C. Pipeline Products & Ongoing Clinical Trials Overview 60
5.25 Moximed Inc Company Overview 62
5.25.1 Moximed Inc Pipeline Products & Ongoing Clinical Trials Overview 62
5.26 Nano Interface Technology LLC (Inactive) Company Overview 67
5.26.1 Nano Interface Technology LLC (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 67
5.27 NovoPedics, Inc. Company Overview 68
5.27.1 NovoPedics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 68
5.28 NuVasive Inc Company Overview 69
5.28.1 NuVasive Inc Pipeline Products & Ongoing Clinical Trials Overview 69
5.29 Ohio State University Company Overview 71
5.29.1 Ohio State University Pipeline Products & Ongoing Clinical Trials Overview 71
5.30 Orthogen LLC Company Overview 72
5.30.1 Orthogen LLC Pipeline Products & Ongoing Clinical Trials Overview 72
5.31 OrthoGrid Systems Company Overview 73
5.31.1 OrthoGrid Systems Pipeline Products & Ongoing Clinical Trials Overview 73
5.32 Orthonika Ltd Company Overview 74
5.32.1 Orthonika Ltd Pipeline Products & Ongoing Clinical Trials Overview 74
5.33 OrthoPathways Group, Inc. Company Overview 75
5.33.1 OrthoPathways Group, Inc. Pipeline Products & Ongoing Clinical Trials Overview 75
5.34 Resultados y Calidad del Sistema Sanitario Publico de Andalucia Company Overview 76
5.34.1 Resultados y Calidad del Sistema Sanitario Publico de Andalucia Pipeline Products & Ongoing Clinical Trials Overview 76
5.35 RIH Orthopaedic Foundation Inc Company Overview 78
5.35.1 RIH Orthopaedic Foundation Inc Pipeline Products & Ongoing Clinical Trials Overview 78
5.36 Sanatmetal Ltd. Company Overview 79
5.36.1 Sanatmetal Ltd. Pipeline Products & Ongoing Clinical Trials Overview 79
5.37 Sensortech Corporation Company Overview 80
5.37.1 Sensortech Corporation Pipeline Products & Ongoing Clinical Trials Overview 80
5.38 Smith & Nephew Plc Company Overview 81
5.38.1 Smith & Nephew Plc Pipeline Products & Ongoing Clinical Trials Overview 81
5.39 Stellenbosch University Company Overview 85
5.39.1 Stellenbosch University Pipeline Products & Ongoing Clinical Trials Overview 85
5.40 University of Florida Company Overview 86
5.40.1 University of Florida Pipeline Products & Ongoing Clinical Trials Overview 86
6 Knee Reconstruction- Recent Developments 87
6.1 Jun 07, 2017: Active Implants SUN Clinical Trial for Persistent Knee Pain Now Underway in San Diego 87
6.2 Jun 06, 2017: 100,000th Robotic-Arm Assisted Joint Replacement Procedure Performed in the U.S. with Stryker's Mako System 87
6.3 Jun 02, 2017: Episurf Medical's Board Names Pal Ryfors New CEO and Appoints New CFO 88
6.4 Jun 01, 2017: DePuy Synthes Launches New ATTUNE Revision Fixed Bearing Tibial Base And Cemented Stem For Primary And Revision Surgeries 88
6.5 May 31, 2017: ATTUNE Knee System Four-Year Revision Rate is Lower Than Total Knee Class, According to New & Independent Joint Registry Data 89
6.6 May 31, 2017: Exactech Announces Successful First Surgeries with Truliant Knee System 90
6.7 May 31, 2017: Depuy Synthes and Ethicon to Showcase Intra Operative Solutions Aiming to Mitigate Surgical Site Infection During Efort Congress 91
6.8 May 25, 2017: Medtronic Reports Fourth Quarter and Fiscal Year 2017 Financial Results 92
6.9 May 24, 2017: MemorialCare Joint Replacement Center At Long Beach Memorial Now Offering Newest Technology In Total Knee Replacement With Stryker's Mako Robotic-Arm Assisted Total Knee Application 95
6.10 May 23, 2017: United Orthopedic Announces First Patient Enrollment In Study Of U2 Knee System 96
6.11 May 23, 2017: OrthoMemphis Performs First Meniscus Replacement in Tennessee with NUsurface Implant 96
6.12 May 23, 2017: Brainlab Chief Financial Officer Joseph Doyle to Retire 98
6.13 May 19, 2017: New advanced therapy to repair cartilage defects in the knee 98
6.14 May 11, 2017: Episurf Medical reaches milestone of 200 implants 99
6.15 May 10, 2017: ConforMIS Reports First Quarter 2017 Financial Results 100
6.16 May 09, 2017: Materialise Reports First Quarter 2017 Results 101
6.17 May 05, 2017: Smith & Nephew 2017 First Quarter Trading Report 102
6.18 May 04, 2017: Orthofix International Reports First Quarter 2017 Financial Results 104
6.19 May 03, 2017: Wright Medical Group Reports 2017 First Quarter Financial Results 105
6.20 May 02, 2017: Onkos Surgical completes first ELEOS Limb Salvage System procedure using uDesign Patient Solutions 108
6.21 May 02, 2017: Brainlab Names New Member of Executive Board 108
6.22 Apr 27, 2017: Advanced Orthopedics & Sports Medicine Specialists Performs First Meniscus Replacements in Colorado with NUsurface Meniscus Implant 108
6.23 Apr 27, 2017: Zimmer Biomet Reports First Quarter 2017 Financial Results 109
6.24 Apr 25, 2017: Stryker reports first quarter 2017 results 110
6.25 Apr 25, 2017: Exactech Q1 Revenue Up 6% to $69.5 Million on 21% Extremities Growth 112
6.26 Apr 21, 2017: New Report Demonstrates The Clinical And Economic Value Of The Attune Knee System In Today's Value-Based Environment 112
6.27 Apr 20, 2017: BioPoly Resurfacing Knee Study Indicates BioPoly Patient Outcomes are Significantly Improved Over Microfracture at 2 Years 114
6.28 Apr 19, 2017: Amedica Announces Delayed Filing of Annual Report on Form 10-K and Receipt of Nasdaq Letter 114
6.29 Apr 18, 2017: Implanet announces Q1 2017 revenue 115
6.30 Apr 12, 2017: ConforMIS Announces Positive Results from Customized iTotal PS Total Knee Replacement Comparative Study 115
6.31 Apr 12, 2017: United Orthopedic Receives U.S. FDA Clearance For U2 Total Knee System E-XPE Insert (CR, PS and UC type) And Patella 116
6.32 Apr 12, 2017: Change in the B. Braun Management Board and the Aesculap Management Board 117
6.33 Apr 06, 2017: MicroPort Orthopedics Announces Launch of its EVOLUTION Revision Tibial System 117
6.34 Apr 06, 2017: MicroPort Orthopedics Announces Launch of its EVOLUTION BioFoam Tibia in US and Europe 117
6.35 Mar 31, 2017: B. Braun continues its sales and earnings growth 118
6.36 Mar 31, 2017: ConforMIS Announces Election of Philip W. Johnston to its Board of Directors 120
6.37 Mar 30, 2017: Exactech New Scientific and Clinical Research Presented at 2017 Orthopaedic Research Society Annual Meeting 120
6.38 Mar 30, 2017: MPSC Announces 2016 Annual Results 121
6.39 Mar 29, 2017: OrthAlign Announces Milestone Achievement 60,000th Joint Arthroplasty Case 122
6.40 Mar 16, 2017: Study Finds Ligament Reconstruction is an Effective Treatment for Kneecap Instability in Patients with Trochlear Dysplasia 123
6.41 Mar 15, 2017: DePuy Synthes Companies Announces New ATTUNE Revision Fixed Bearing Tibial Base and Cemented Stem for Primary and Revision Surgeries 124
6.42 Mar 14, 2017: Stryker enabling surgeons to have a more predictable surgical experience with launch of Mako robotic-arm assisted total knee application 124
6.43 Mar 14, 2017: Smith & Nephew previews NAVIO Robotics-assisted Total Knee Application at AAOS ahead of full market release in Q2 2017 125
6.44 Mar 14, 2017: Zimmer Biomet Showcases New Product Innovation, Novel Digital Health Offering and Robotic Technology at AAOS 2017 125
6.45 Mar 14, 2017: Medacta Helps Hospitals and Surgeons Go "All In" on Outpatient Care 127
6.46 Mar 14, 2017: Arthrex Welcomes Mark Ferguson, MD, as Director of Medical Education, Asia-Pacific (APAC) Region 128
6.47 Mar 13, 2017: Exactech Announces Full Launch of Three Revision Systems and Expansion of Advanced Surgical Technologies at AAOS 2017 Annual Meeting, Exhibit 1433 129
6.48 Mar 09, 2017: Bionik Laboratories Provides Company Highlights 129
6.49 Mar 06, 2017: OrthAlign Announces Full Commercial Launch of UniAlign, the world's first handheld navigation device for use in Unicompartmental Knee Arthroplasty 130
6.50 Mar 01, 2017: MicroPort Orthopedics Announces Results of Clinical Outcome Study Demonstrating 98.8% Implant Survivorship of its Medial-Pivot Knee System at 17 Years 131
6.51 Mar 01, 2017: OrthAlign Appoints Eric B. Timko As New Chief Executive Officer and Chairman of the Board 131
6.52 Feb 27, 2017: Bionik Laboratories Appoints Malcolm G. Bock as Vice President of Engineering 132
6.53 Feb 27, 2017: Amedica Announces Results of Independent Femoral Head Wear Testing 132
6.54 Feb 27, 2017: Orthofix International Reports Fourth Quarter and Fiscal 2016 Financial Results 133
6.55 Feb 22, 2017: Active Implants Appoints Ted Davis President and Chief Executive Officer 134
6.56 Feb 22, 2017: Change in the B. Braun Management Board 135
6.57 Feb 21, 2017: Medtronic Reports Third Quarter Financial Results 135
6.58 Feb 21, 2017: Wright Medical Group Reports 2016 Fourth Quarter and Full-Year Financial Results and Provides 2017 Guidance 138
6.59 Feb 21, 2017: Exactech 2016 Revenue Up 7% to $257.6 Million, Q4'16 Revenue Increased 6% to $66.2 Million 140
6.60 Feb 20, 2017: Surgeons use metal nail and remote-controlled magnet to help treat knee arthritis 142
6.61 Feb 15, 2017: Bionik Laboratories Reports Third Quarter Fiscal Year 2017 Financial Results 143
6.62 Feb 09, 2017: Arlington Orthopedic Associates, P.A. Performs First Meniscus Replacements in Texas with NUsurface Meniscus Implant 144
6.63 Feb 09, 2017: Smith & Nephew Fourth Quarter Trading and Full Year 2016 Results 145
6.64 Feb 09, 2017: Smith & Nephew: Directorate Change 151
6.65 Feb 06, 2017: Medtronic Awarded U.S. Department of Veterans Affairs National Contracts for Home Telehealth Technologies, with Three Other Vendors 151
6.66 Feb 01, 2017: Medacta USA's Spine Division Begins 2017 with Key Appointment, Significant Growth 152
6.67 Jan 31, 2017: Zimmer Biomet Reports Fourth Quarter and Full-Year 2016 Financial Results 152
6.68 Jan 31, 2017: OrthAlign Continues Impressive Worldwide Growth in 2016, Including Milestone Achievement 56,000th Joint Arthroplasty Case 153
6.69 Jan 24, 2017: Stryker reports 2016 results and 2017 outlook 154
6.70 Jan 18, 2017: Orthofix Announces Resolution of SEC Investigations 156
6.71 Jan 17, 2017: Zimmer Biomet Announces Americas Leadership Transition 156
6.72 Jan 17, 2017: Corin welcomes Elvio Gramignano 157
6.73 Jan 16, 2017: Implanet Reports 2016 Sales Growth of +18% to 7.8 Million 157
6.74 Jan 12, 2017: Zimmer Biomet Announces Resolution with DOJ and SEC Regarding Previously Disclosed Legacy Biomet FCPA Matters 158
6.75 Jan 12, 2017: Confirmation of CFO leaving Smith & Nephew 159
6.76 Jan 10, 2017: Stryker provides 2016 preliminary net sales results 159
6.77 Jan 10, 2017: Zimmer Biomet Announces Fourth Quarter and Full-Year 2016 Preliminary Sales Results 160
6.78 Jan 10, 2017: Orthofix Announces Preliminary 2016 Fourth Quarter and Full Year Net Sales Results 161
6.79 Jan 09, 2017: First Evolution Total Knee Replacement Completed in Heilongjiang Province 161
7 Appendix 260
7.1 Methodology 260
7.2 About GlobalData 263
7.3 Contact Us 263
7.4 Disclaimer 263
1.1 List of Tables
Table 1: Knee Reconstruction - Pipeline Products by Stage of Development 14
Table 2: Knee Reconstruction - Pipeline Products by Segment 15
Table 3: Knee Reconstruction - Pipeline Products by Territory 16
Table 4: Knee Reconstruction - Pipeline Products by Regulatory Path 17
Table 5: Knee Reconstruction - Pipeline Products by Estimated Approval Date 18
Table 6: Knee Reconstruction - Ongoing Clinical Trials 19
Table 7: Knee Reconstruction Companies - Pipeline Products by Stage of Development 20
Table 8: Knee Reconstruction - Pipeline Products by Stage of Development 22
Table 9: 4-Web Spine, LLC Pipeline Products & Ongoing Clinical Trials Overview 24
Table 10: Truss Implant - Knee Procedures - Product Status 24
Table 11: Truss Implant - Knee Procedures - Product Description 24
Table 12: Active Implants LLC Pipeline Products & Ongoing Clinical Trials Overview 25
Table 13: NUsurface Meniscus Implant - Product Status 25
Table 14: NUsurface Meniscus Implant - Product Description 25
Table 15: Active Implants LLC - Ongoing Clinical Trials Overview 26
Table 16: NUsurface Meniscus Implant - The SUN Clinical Trial (Safety Utilizing NUsurface Meniscus Implant). A Multi-center, Single-arm, Prospective, Open-label, Non-randomized, Observational Clinical Study 27
Table 17: NUsurface Meniscus Implant - The VENUS Clinical Study (Verifying the Effectiveness of the NUsurface System) A Multi-center, Prospective, Randomized, Interventional, Superiority Clinical Study 27
Table 18: NUsurface Meniscus Implant - The VENUS Clinical Study (Verifying the Effectiveness of the NUsurface System) A Multi-centered, Prospective, Randomized, Interventional, Superiority Clinical Study 27
Table 19: NUsurface Meniscus Implant - Treatment of the Medial Meniscus with the Nusurface Meniscus Implant 28
Table 20: Amedica Corp Pipeline Products & Ongoing Clinical Trials Overview 29
Table 21: Infinia Total Knee Implant - Product Status 29
Table 22: Infinia Total Knee Implant - Product Description 29
Table 23: Arcuro Medical Ltd. Pipeline Products & Ongoing Clinical Trials Overview 30
Table 24: SuperBall Repair System - Product Status 30
Table 25: SuperBall Repair System - Product Description 30
Table 26: ArthroSurface Inc Pipeline Products & Ongoing Clinical Trials Overview 31
Table 27: HemiCAP Femoral Condyle - Product Status 31
Table 28: HemiCAP Femoral Condyle - Product Description 31
Table 29: Artimplant AB (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 32
Table 30: Knee Resurfacing Implant - Product Status 32
Table 31: Knee Resurfacing Implant - Product Description 32
Table 32: Aspect Biosystems Ltd Pipeline Products & Ongoing Clinical Trials Overview 33
Table 33: Bioprinted Knee Meniscus Tissue - Product Status 33
Table 34: Bioprinted Knee Meniscus Tissue - Product Description 33
Table 35: B. Braun Melsungen AG Pipeline Products & Ongoing Clinical Trials Overview 34
Table 36: Biological Knee Regeneration Device - Product Status 34
Table 37: Biological Knee Regeneration Device - Product Description 34
Table 38: BioPoly RS LLC Pipeline Products & Ongoing Clinical Trials Overview 35
Table 39: BioPoly RS Partial Resurfacing Knee Implant System - Product Status 35
Table 40: BioPoly RS Partial Resurfacing Knee Implant System - Product Description 35
Table 41: Bonovo Orthopedics Inc Pipeline Products & Ongoing Clinical Trials Overview 36
Table 42: JMM Total Knee System - Product Status 36
Table 43: JMM Total Knee System - Product Description 36
Table 44: Clemson University Pipeline Products & Ongoing Clinical Trials Overview 37
Table 45: Engage Knee System - Product Status 37
Table 46: Engage Knee System - Product Description 37
Table 47: Total Knee Replacement Device - Product Status 38
Table 48: Total Knee Replacement Device - Product Description 38
Table 49: Corin Group Plc Pipeline Products & Ongoing Clinical Trials Overview 39
Table 50: IL-Knee - Product Status 39
Table 51: IL-Knee - Product Description 39
Table 52: IL-Knee 1 - Product Status 40
Table 53: IL-Knee 1 - Product Description 40
Table 54: IL-Knee 2 - Product Status 40
Table 55: IL-Knee 2 - Product Description 40
Table 56: Uniglide Mobile Bearing Unicondylar Knee System - Product Status 41
Table 57: Uniglide Mobile Bearing Unicondylar Knee System - Product Description 41
Table 58: Ecole de technologie superieure Pipeline Products & Ongoing Clinical Trials Overview 42
Table 59: Knee Resurfacing Implant - Product Status 42
Table 60: Knee Resurfacing Implant - Product Description 42
Table 61: Exactech Inc Pipeline Products & Ongoing Clinical Trials Overview 43
Table 62: Adv. Ligament Balancing System - Product Status 43
Table 63: Adv. Ligament Balancing System - Product Description 44
Table 64: Exactech GPS CC System - Product Status 44
Table 65: Exactech GPS CC System - Product Description 44
Table 66: Exactech GPS Uni System - Product Status 45
Table 67: Exactech GPS Uni System - Product Description 45
Table 68: One Logic Patella System - Product Status 45
Table 69: One Logic Patella System - Product Description 45
Table 70: Optetrak Logic RBK System - Product Status 46
Table 71: Optetrak Logic RBK System - Product Description 46
Table 72: Optetrak Logic Unicondylar System - Product Status 46
Table 73: Optetrak Logic Unicondylar System - Product Description 47
Table 74: EZ ORTHOPEDICS ISRAEL Pipeline Products & Ongoing Clinical Trials Overview 48
Table 75: EZ KneeSpan - Product Status 48
Table 76: EZ KneeSpan - Product Description 48
Table 77: Hospital for Special Surgery Pipeline Products & Ongoing Clinical Trials Overview 49
Table 78: Locking Mechanism Device For Tibial Component - Product Status 49
Table 79: Locking Mechanism Device For Tibial Component - Product Description 49
Table 80: Revision Knee System - Product Status 50
Table 81: Revision Knee System - Product Description 50
Table 82: Indian Institute of Technology Bombay Pipeline Products & Ongoing Clinical Trials Overview 51
Table 83: Modular Knee Joint Implant - Product Status 51
Table 84: Modular Knee Joint Implant - Product Description 51
Table 85: Invibio Inc Pipeline Products & Ongoing Clinical Trials Overview 52
Table 86: PEEK-OPTIMA Femoral Knee Replacement Device - Product Status 52
Table 87: PEEK-OPTIMA Femoral Knee Replacement Device - Product Description 52
Table 88: Kinamed Inc Pipeline Products & Ongoing Clinical Trials Overview 53
Table 89: GEM - Total Knee System - Product Status 53
Table 90: GEM - Total Knee System - Product Description 53
Table 91: KYOCERA Medical Corp Pipeline Products & Ongoing Clinical Trials Overview 54
Table 92: Artificial Knee - Product Status 54
Table 93: Artificial Knee - Product Description 54
Table 94: Materialise NV Pipeline Products & Ongoing Clinical Trials Overview 55
Table 95: X-ray Knee Guide System - Product Status 55
Table 96: X-ray Knee Guide System - Product Description 55
Table 97: Materialise NV - Ongoing Clinical Trials Overview 56
Table 98: X-ray Knee Guide System - Prospective Monocentric Clinical Investigation Using the Materialise X-ray Knee Guides for Total Knee Arthroplast 56
Table 99: Mathys AG Bettlach Pipeline Products & Ongoing Clinical Trials Overview 57
Table 100: BalanSys Vitamys CR - Product Status 57
Table 101: BalanSys Vitamys CR - Product Description 57
Table 102: MicroPort Scientific Corp Pipeline Products & Ongoing Clinical Trials Overview 58
Table 103: EVOLUTION BIOFOAM Tibial System - Product Status 58
Table 104: EVOLUTION BIOFOAM Tibial System - Product Description 59
Table 105: EVOLUTION Revision CCK Femur And Insert - Product Status 59
Table 106: EVOLUTION Revision CCK Femur And Insert - Product Description 59
Table 107: Moirai Orthopaedics, L.L.C. Pipeline Products & Ongoing Clinical Trials Overview 60
Table 108: Pyrocarbon Implant Replacement System - Product Status 60
Table 109: Pyrocarbon Implant Replacement System - Product Description 60
Table 110: Moirai Orthopaedics, L.L.C. - Ongoing Clinical Trials Overview 61
Table 111: Pyrocarbon Implant Replacement System - Safety and Efficacy of the Pyrocarbon Implant Replacement (PIR) System 61
Table 112: Moximed Inc Pipeline Products & Ongoing Clinical Trials Overview 62
Table 113: Atlas Knee System - Product Status 62
Table 114: Atlas Knee System - Product Description 62
Table 115: KineSpring Knee Implant System - Product Status 63
Table 116: KineSpring Knee Implant System - Product Description 63
Table 117: Moximed Inc - Ongoing Clinical Trials Overview 64
Table 118: KineSpring Knee Implant System - Global, Prospective, Multi-center, Non-randomized, Controlled Non-inferiority Trial to Evaluate Symptom Relief in Patients with Medial Knee Osteoarthritis Treated with the KineSpring Knee Implant for Load Reduction Compared to HTO 65
Table 119: KineSpring Knee Implant System - Prospective, Multi-center, Pilot Study to Evaluate Symptom Relief in Patients with Medial Knee Osteoarthritis (OA) Treated with the Kinespring Knee Implant for Load Reduction 65
Table 120: Atlas Knee System - Feasibility of the Phantom Knee System in Improving Pain Relief and Function in Patients Needing Unloading of the Medial Compartment of the Knee: A Prospective, Multi-center, Single-arm First in Human Study 66
Table 121: Atlas Knee System - Prospective, Multi-center, Single Arm, Pilot Study to Evaluate Symptom Relief in Subjects with Medial Knee Osteoarthritis Treated with the Atlas Knee System for Load Reduction 66
Table 122: Nano Interface Technology LLC (Inactive) Pipeline Products & Ongoing Clinical Trials Overview 67
Table 123: Knee Implant - Product Status 67
Table 124: Knee Implant - Product Description 67
Table 125: NovoPedics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 68
Table 126: Meniscofix - Product Status 68
Table 127: Meniscofix - Product Description 68
Table 128: NuVasive Inc Pipeline Products & Ongoing Clinical Trials Overview 69
Table 129: PRECICE OPTY-LINE System - Product Status 69
Table 130: PRECICE OPTY-LINE System - Product Description 69
Table 131: NuVasive Inc - Ongoing Clinical Trials Overview 70
Table 132: PRECICE OPTY-LINE System - Clinical Evaluation of Nuvasive PRECICE OPTY-LINE System in Europe 70
Table 133: Ohio State University Pipeline Products & Ongoing Clinical Trials Overview 71
Table 134: Joint Stability Measurement Device - Product Status 71
Table 135: Joint Stability Measurement Device - Product Description 71
Table 136: Orthogen LLC Pipeline Products & Ongoing Clinical Trials Overview 72
Table 137: Neural Limb Prosthesis Device - Product Status 72
Table 138: Neural Limb Prosthesis Device - Product Description 72
Table 139: OrthoGrid Systems Pipeline Products & Ongoing Clinical Trials Overview 73
Table 140: KneeFXGrid - Product Status 73
Table 141: KneeFXGrid - Product Description 73
Table 142: Orthonika Ltd Pipeline Products & Ongoing Clinical Trials Overview 74
Table 143: Synthetic Meniscus - Product Status 74
Table 144: Synthetic Meniscus - Product Description 74
Table 145: OrthoPathways Group, Inc. Pipeline Products & Ongoing Clinical Trials Overview 75
Table 146: Stamina Knee System - Product Status 75
Table 147: Stamina Knee System - Product Description 75
Table 148: Resultados y Calidad del Sistema Sanitario Publico de Andalucia Pipeline Products & Ongoing Clinical Trials Overview 76
Table 149: Knee Replacement Implant - Product Status 76
Table 150: Knee Replacement Implant - Product Description 76
Table 151: Secondary Knee Prosthesis - Product Status 77
Table 152: Secondary Knee Prosthesis - Product Description 77
Table 153: RIH Orthopaedic Foundation Inc Pipeline Products & Ongoing Clinical Trials Overview 78
Table 154: TruTarget System - Product Status 78
Table 155: TruTarget System - Product Description 78
Table 156: Sanatmetal Ltd. Pipeline Products & Ongoing Clinical Trials Overview 79
Table 157: Sanatmetal's Knee Joint Replacement System - Product Status 79
Table 158: Sanatmetal's Knee Joint Replacement System - Product Description 79
Table 159: Sensortech Corporation Pipeline Products & Ongoing Clinical Trials Overview 80
Table 160: Force Check Knee Replacement Smart Insert - Product Status 80
Table 161: Force Check Knee Replacement Smart Insert - Product Description 80
Table 162: Smith & Nephew Plc Pipeline Products & Ongoing Clinical Trials Overview 81
Table 163: LEGION RH Hinge - Product Status 81
Table 164: LEGION RH Hinge - Product Description 81
Table 165: NAVIO Surgical System With GENESIS II - Product Status 82
Table 166: NAVIO Surgical System With GENESIS II - Product Description 82
Table 167: NAVIO Surgical System With JOURNEY II - Product Status 82
Table 168: NAVIO Surgical System With JOURNEY II - Product Description 83
Table 169: NAVIO Surgical System With LEGION - Product Status 83
Table 170: NAVIO Surgical System With LEGION - Product Description 83
Table 171: Robotics-Assisted Revision Knee System - Product Status 84
Table 172: Robotics-Assisted Revision Knee System - Product Description 84
Table 173: Stellenbosch University Pipeline Products & Ongoing Clinical Trials Overview 85
Table 174: uMove - Product Status 85
Table 175: uMove - Product Description 85
Table 176: University of Florida Pipeline Products & Ongoing Clinical Trials Overview 86
Table 177: Spacer Block With Sensor - Product Status 86
Table 178: Spacer Block With Sensor - Product Description 86
Table 179: Glossary 262
1.2 List of Figures
Figure 1: Knee Reconstruction - Pipeline Products by Stage of Development 14
Figure 2: Knee Reconstruction - Pipeline Products by Segment 15
Figure 3: Knee Reconstruction - Pipeline Products by Territory 16
Figure 4: Knee Reconstruction - Pipeline Products by Regulatory Path 17
Figure 5: Knee Reconstruction - Pipeline Products by Estimated Approval Date 18
Figure 6: Knee Reconstruction - Ongoing Clinical Trials 19
