Published : Apr-2017
No. of Pages : 106
1 Table of Contents 2
1.1 List of Tables 5
1.2 List of Figures 6
2 Introduction 7
2.1 Orthopedic Bone Cement Overview 7
3 Products under Development 8
3.1 Orthopedic Bone Cement - Pipeline Products by Stage of Development 8
3.2 Orthopedic Bone Cement - Pipeline Products by Segment 9
3.3 Orthopedic Bone Cement - Pipeline Products by Territory 10
3.4 Orthopedic Bone Cement - Pipeline Products by Regulatory Path 11
3.5 Orthopedic Bone Cement - Pipeline Products by Estimated Approval Date 12
4 Orthopedic Bone Cement - Pipeline Products under Development by Companies 13
4.1 Orthopedic Bone Cement Companies - Pipeline Products by Stage of Development 13
4.2 Orthopedic Bone Cement - Pipeline Products by Stage of Development 14
5 Orthopedic Bone Cement Companies and Product Overview 15
5.1 aap Implantate AG Company Overview 15
5.1.1 aap Implantate AG Pipeline Products & Ongoing Clinical Trials Overview 15
5.2 Biofix Medical Technologies Company Overview 17
5.2.1 Biofix Medical Technologies Pipeline Products & Ongoing Clinical Trials Overview 17
5.3 Bone-Rad Therapeutics, Inc. Company Overview 18
5.3.1 Bone-Rad Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 18
5.4 DePuy Synthes Inc Company Overview 19
5.4.1 DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 19
5.5 Exactech Inc Company Overview 20
5.5.1 Exactech Inc Pipeline Products & Ongoing Clinical Trials Overview 20
5.6 Graftys SA Company Overview 21
5.6.1 Graftys SA Pipeline Products & Ongoing Clinical Trials Overview 21
5.7 Meta Biomed Co Ltd Company Overview 23
5.7.1 Meta Biomed Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 23
5.8 Onbone Oy Company Overview 24
5.8.1 Onbone Oy Pipeline Products & Ongoing Clinical Trials Overview 24
5.9 Osseon Therapeutics Inc Company Overview 25
5.9.1 Osseon Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 25
5.10 Ozics AG Company Overview 26
5.10.1 Ozics AG Pipeline Products & Ongoing Clinical Trials Overview 26
5.11 Queen's University Belfast Company Overview 28
5.11.1 Queen's University Belfast Pipeline Products & Ongoing Clinical Trials Overview 28
5.12 Sree Chitra Tirunal Institute for Medical Sciences & Technology Company Overview 29
5.12.1 Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 29
5.13 Teknimed SA Company Overview 32
5.13.1 Teknimed SA Pipeline Products & Ongoing Clinical Trials Overview 32
5.14 University of Limerick Company Overview 34
5.14.1 University of Limerick Pipeline Products & Ongoing Clinical Trials Overview 34
5.15 Zimmer Biomet Holdings Inc Company Overview 36
5.15.1 Zimmer Biomet Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 36
6 Orthopedic Bone Cement- Recent Developments 37
6.1 Mar 21, 2017: Medtronic Prices Public Offering of 1.7% Notes Due 2019 for USD1 Billion 37
6.2 Mar 21, 2017: Medtronic Prices Public Offering of 3.35% Notes Due 2027 for USD850 Million 37
6.3 Mar 21, 2017: Medtronic Prices Public Offering of 4.625% Notes Due 2045 for USD150 Million 38
6.4 Mar 15, 2017: Alphatec Holdings Announces Fourth Quarter and Full Year 2016 Financial Results 38
6.5 Mar 14, 2017: Medtronic Announces New Bone Cement Indication for Treating Sacral Fractures 39
6.6 Mar 08, 2017: DJO Global Announces Financial Results for Fourth Quarter and Fiscal Year End 2016 40
6.7 Mar 01, 2017: DJO Global Announces Appointment of Bryan McMillan as President, Regeneration 43
6.8 Feb 21, 2017: Medtronic Reports Third Quarter Financial Results 43
6.9 Feb 21, 2017: Exactech 2016 Revenue Up 7% to $257.6 Million, Q4'16 Revenue Increased 6% to $66.2 Million 46
6.10 Feb 14, 2017: Alphatec Spine Announces Appointment of David H. Mowry to its Board of Directors 48
6.11 Feb 09, 2017: Smith & Nephew Fourth Quarter Trading and Full Year 2016 Results 48
6.12 Feb 09, 2017: Smith & Nephew: Directorate Change 54
6.13 Feb 06, 2017: Medtronic Awarded U.S. Department of Veterans Affairs National Contracts for Home Telehealth Technologies, with Three Other Vendors 54
6.14 Jan 31, 2017: Zimmer Biomet Reports Fourth Quarter and Full-Year 2016 Financial Results 55
6.15 Jan 24, 2017: Stryker reports 2016 results and 2017 outlook 56
6.16 Jan 17, 2017: Zimmer Biomet Announces Americas Leadership Transition 57
6.17 Jan 12, 2017: Stryker Prices Public Offering of 1.800% Notes Due 2019 for USD500 Million 58
6.18 Jan 12, 2017: Zimmer Biomet Announces Resolution with DOJ and SEC Regarding Previously Disclosed Legacy Biomet FCPA Matters 58
6.19 Jan 12, 2017: Confirmation of CFO leaving Smith & Nephew 58
6.20 Jan 10, 2017: Stryker provides 2016 preliminary net sales results 59
6.21 Jan 10, 2017: Zimmer Biomet Announces Fourth Quarter and Full-Year 2016 Preliminary Sales Results 60
6.22 Dec 14, 2016: Zimmer Biomet Update on Product Supply Matters and Responsive Statement on Recently Completed FDA Inspection 61
6.23 Dec 12, 2016: Alphatec Holdings appoints new CEO 61
6.24 Dec 12, 2016: Alphatec Holdings Announces Board and Executive Leadership Changes 62
6.25 Nov 30, 2016: Graham Baker appointed Chief Financial Officer 65
6.26 Nov 22, 2016: Medtronic Reports Second Quarter Financial Results 65
6.27 Nov 16, 2016: Medtronic Releases FY16 Integrated Performance Report 68
6.28 Nov 15, 2016: CEVA to work with Medtronic for distribution facility construction 69
6.29 Nov 14, 2016: DJO Global Announces Appointment of Brady Shirley as President and Chief Executive Officer 69
6.30 Nov 09, 2016: Alphatec Holdings Announces Third Quarter 2016 Revenue and Financial Results 70
6.31 Nov 08, 2016: DJO Global Announces Financial Results for Third Quarter 73
6.32 Nov 03, 2016: Smith & Nephew Third Quarter 2016 Trading Report 74
6.33 Oct 31, 2016: Zimmer Biomet Reports Third Quarter 2016 Financial Results 76
6.34 Oct 31, 2016: Exactech Q3 Revenue Up 7% to $59.9 Million. Net Income up 10% to $3.2 Million. Diluted EPS $0.22 vs. $0.20. 77
6.35 Oct 27, 2016: Stryker reports third quarter 2016 results 78
6.36 Oct 05, 2016: Alphatec Holdings Announces Company Updates 79
6.37 Sep 15, 2016: Alphatec Holdings Announces Company Updates 80
6.38 Sep 15, 2016: Medtronic Names Mark Ploof Senior Vice President of Global Operations and Business Services 82
6.39 Sep 06, 2016: DJO Global Announces Appointment of Mike Eklund as Chief Operating Officer and Chief Financial Officer 82
6.40 Aug 25, 2016: Medtronic Reports First Quarter Financial Results 83
6.41 Aug 01, 2016: Exactech Q2 Revenue Up 8% to $66.1 Million; Net Income up 20% to $4.4 Million; Diluted EPS $0.31 vs. $0.26 86
6.42 Jul 28, 2016: Smith & Nephew Second Quarter Trading and First Half 2016 Results 87
6.43 Jul 28, 2016: Zimmer Biomet Reports Second Quarter 2016 Financial Results 90
6.44 Jul 28, 2016: DJO Global Announces Financial Results for Second Quarter 2016 91
6.45 Jul 21, 2016: Stryker reports second quarter 2016 results 92
6.46 Jul 11, 2016: CFO to leave Smith & Nephew in early 2017 93
6.47 Jul 06, 2016: Merit Medical Systems Acquires DFINE for USD97.5 Million 94
6.48 Jun 30, 2016: NuVasive Agrees to Settle Patent Litigation With Medtronic 94
6.49 Jun 13, 2016: Zimmer Biomet Raises USD1.28 Billion in Public Offering of Shares 95
6.50 Jun 07, 2016: Zimmer Biomet Raises USD532 Million in Public Offering of 2.42% Notes Due 2026 95
6.51 Jun 07, 2016: Zimmer Biomet Raises USD532 Million in Public Offering of 1.4% Notes Due 2022 96
6.52 Jun 06, 2016: Medtronic Outlines Future Growth Vision at Investor Day 96
6.53 Jun 01, 2016: Osseon Expands Its Independent Distribution Network 97
6.54 May 31, 2016: Medtronic Reports Fourth Quarter and Fiscal Year 2016 Financial Results 97
6.55 May 10, 2016: DJO Global Announces Financial Results for First Quarter 2016 100
6.56 Apr 20, 2016: Stryker reports first quarter 2016 results 101
6.57 Mar 31, 2016: GRAFTYS strengthens its management and operations 102
7 Appendix 103
7.1 Methodology 103
7.2 About GlobalData 106
7.3 Contact Us 106
7.4 Disclaimer 106
1.1 List of Tables
Table 1: Orthopedic Bone Cement - Pipeline Products by Stage of Development 8
Table 2: Orthopedic Bone Cement - Pipeline Products by Segment 9
Table 3: Orthopedic Bone Cement - Pipeline Products by Territory 10
Table 4: Orthopedic Bone Cement - Pipeline Products by Regulatory Path 11
Table 5: Orthopedic Bone Cement - Pipeline Products by Estimated Approval Date 12
Table 6: Bone Cement Companies - Pipeline Products by Stage of Development 13
Table 7: Orthopedic Bone Cement - Pipeline Products by Stage of Development 14
Table 8: aap Implantate AG Pipeline Products & Ongoing Clinical Trials Overview 15
Table 9: Ag Cement - Product Status 15
Table 10: Ag Cement - Product Description 16
Table 11: Biofix Medical Technologies Pipeline Products & Ongoing Clinical Trials Overview 17
Table 12: Injectable Glass Ionomer Cement - Product Status 17
Table 13: Injectable Glass Ionomer Cement - Product Description 17
Table 14: Bone-Rad Therapeutics, Inc. Pipeline Products & Ongoing Clinical Trials Overview 18
Table 15: Spine-Rad Brachytherapy Bone Cement - Product Status 18
Table 16: Spine-Rad Brachytherapy Bone Cement - Product Description 18
Table 17: DePuy Synthes Inc Pipeline Products & Ongoing Clinical Trials Overview 19
Table 18: Statin Eluting Bone Cements - Product Status 19
Table 19: Statin Eluting Bone Cements - Product Description 19
Table 20: Exactech Inc Pipeline Products & Ongoing Clinical Trials Overview 20
Table 21: Bone Cement - Product Status 20
Table 22: Bone Cement - Product Description 20
Table 23: Graftys SA Pipeline Products & Ongoing Clinical Trials Overview 21
Table 24: GRFT-M03 - Product Status 21
Table 25: GRFT-M03 - Product Description 21
Table 26: GRFT-M05 - Product Status 22
Table 27: GRFT-M05 - Product Description 22
Table 28: Meta Biomed Co Ltd Pipeline Products & Ongoing Clinical Trials Overview 23
Table 29: Bone Cement - Product Status 23
Table 30: Bone Cement - Product Description 23
Table 31: Onbone Oy Pipeline Products & Ongoing Clinical Trials Overview 24
Table 32: BIOCEMENT - Product Status 24
Table 33: BIOCEMENT - Product Description 24
Table 34: Osseon Therapeutics Inc Pipeline Products & Ongoing Clinical Trials Overview 25
Table 35: Monetite - Based Injectable Orthopaedic Cement - Product Status 25
Table 36: Monetite - Based Injectable Orthopaedic Cement - Product Description 25
Table 37: Ozics AG Pipeline Products & Ongoing Clinical Trials Overview 26
Table 38: CompO6 Bone Reinforcement Composite - Product Status 26
Table 39: CompO6 Bone Reinforcement Composite - Product Description 26
Table 40: CompO6 Reinforced Bone Composite - Osteoporotic Fractures - Product Status 27
Table 41: CompO6 Reinforced Bone Composite - Osteoporotic Fractures - Product Description 27
Table 42: Queen's University Belfast Pipeline Products & Ongoing Clinical Trials Overview 28
Table 43: Spinal Cement - Product Status 28
Table 44: Spinal Cement - Product Description 28
Table 45: Sree Chitra Tirunal Institute for Medical Sciences & Technology Pipeline Products & Ongoing Clinical Trials Overview 29
Table 46: BioCaS - Product Status 29
Table 47: BioCaS - Product Description 29
Table 48: Bone Cement - Product Status 30
Table 49: Bone Cement - Product Description 30
Table 50: Injectable Calcium Phosphate Cement - Product Status 30
Table 51: Injectable Calcium Phosphate Cement - Product Description 31
Table 52: Teknimed SA Pipeline Products & Ongoing Clinical Trials Overview 32
Table 53: Cemfix 1 - Product Status 32
Table 54: Cemfix 1 - Product Description 32
Table 55: Cemfix 3 - Product Status 33
Table 56: Cemfix 3 - Product Description 33
Table 57: University of Limerick Pipeline Products & Ongoing Clinical Trials Overview 34
Table 58: Bioactive Adhesive Cement - Product Status 34
Table 59: Bioactive Adhesive Cement - Product Description 34
Table 60: Dual Calcium Phosphate Paste System - Product Status 34
Table 61: Dual Calcium Phosphate Paste System - Product Description 35
Table 62: Heracap - Product Status 35
Table 63: Heracap - Product Description 35
Table 64: Zimmer Biomet Holdings Inc Pipeline Products & Ongoing Clinical Trials Overview 36
Table 65: Cobalt Stage One Acrylic Spacer Cement - Product Status 36
Table 66: Cobalt Stage One Acrylic Spacer Cement - Product Description 36
Table 67: Glossary 105
1.2 List of Figures
Figure 1: Orthopedic Bone Cement - Pipeline Products by Stage of Development 8
Figure 2: Orthopedic Bone Cement - Pipeline Products by Segment 9
Figure 3: Orthopedic Bone Cement - Pipeline Products by Territory 10
Figure 4: Orthopedic Bone Cement - Pipeline Products by Regulatory Path 11
Figure 5: Orthopedic Bone Cement - Pipeline Products by Estimated Approval Date 12
